Friday, December 12, 2014

Obesity Cured with our Good Friends Mice

 Obesity Cured with our Good Friends Mice
Scientists are doing a whole lot of experiments with mice lately; it's a norm for medical researchers. I'm pretty sure an obese mouse that has been experimented on with super hormone drugs that make them healthier and lose weight isn't animal cruelty, but who knows what they do with them. I have to say they really do a lot of good work with mice though, researchers from Indiana University and the German Research Center for Environmental Health have practically cured obesity, onset diabetes and lipid abnormalities associated to those health problems. I hope you know your chemistry and health because this will get a tiny bit complicated. By using three different gastrointestinal hormones and combining them into one peptide molecule which they call a triple agonist they were able to make a new molecule that super activates basically natural dieting from your body. It consists of two endocrine hormones GLP-1 which increases insulin action and curbs appetite, GIP which reduces blood glucose and finally glucagon which increases the long term rate calories burn and improves liver function. They will do human trials soon and most likely it will work and could possibly be used by physicians and doctors as new alternative treatment for different glucose and obesity related medical illnesses. The peptide is also the first rationally designed, fully potent and balanced triple agonist ever achieved in the treatment of any disease says DiMarchi one of the men who co-led the study. That has to come with a Guinness world record in genetic science or chemistry. Before they only used two hormones to make more commonly a co-agonist molecule from just GLP-1 and GIP.
 I find this breakthrough really good news because it controls metabolism at an efficient rate and well makes them super powerful. It reminds me of when Captain America can’t get drunk because his metabolism is too fast, and how his liver will probably never fail because of it too. I think this peptide could possibly give you similar effects if it was incredibly powerful and maybe it can prevent alcoholics and obese people from dying from liver failure. I also think this will be greatly effective for diabetes and patients wouldn’t have to take a lot of insulin. This also gives people with genes that naturally make their metabolism slow a chance to have a faster metabolism and eat more without worrying about weight. I wonder what competitive eater wouldn’t use it to keep their weight under control to fit more food in their stretched out stomachs. Then again the fastest hot dog eaters are already not that overweight and one of the most famous is a pretty skinny Japanese guy. The thing is they work to increase the size of their stomachs and must have a killer metabolism and digestive system that can handle all that fast food, but that’s just plain rare for a lot of people like me. I wish I had a high metabolism and I bet a lot of other people do so I wouldn’t mind trying this out in the distant future when I want to try splurging and eating competitions. I think this also might help Hepatitis B patients from liver failure because the disease attacks the liver, but will probably be a little bit effective if the disease is stronger.
By the way I hope they didn't have a lot of dead obese mice and rats though to make this possible. It would kind of make me sad for mice because how unhappy would mice feel while being so chubby they can't move, being tested on with drugs, being forced to eat more food and being dead. They kind of look like water balloons.

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